Frequently Asked Questions (FAQ)
Genetic Testing
What is PGT-A and why is it recommended?
PGT-A (Preimplantation Genetic Testing for Aneuploidies) is a laboratory test performed on embryos created during IVF before they are transferred to the uterus. It screens each embryo’s chromosomes to identify abnormalities that would cause implantation failure, miscarriage, or chromosomal conditions such as Down syndrome. Transferring only chromosomally normal (euploid) embryos significantly improves IVF success rates and reduces miscarriage risk.
Who should consider PGT-A testing?
PGT-A is particularly recommended for women over 35, couples with recurrent IVF failure, those who have experienced recurrent miscarriage, couples with a known chromosomal condition, and those undergoing family balancing. It can also be beneficial for any couple who wants to maximize the chance of success per embryo transfer.
Does the embryo biopsy for PGT-A harm the embryo?
The biopsy involves removing 4–8 cells from the outer layer of the blastocyst (trophectoderm) — cells that would form the placenta, not the baby itself. Multiple studies confirm this does not harm the embryo’s developmental potential. The procedure is performed by highly trained embryologists and is considered safe with minimal risk.
